Implication of xanthine oxidase-inhibiting therapy for non-gouty conditions
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چکیده
منابع مشابه
Comparison of Xanthine Oxidase Inhibitors in Gouty Patients with Hyperuricemia
Objective: Febuxostat is more effective/superior to Allopurinol in reducing the serum uric acid (SUA) level in the treatment of hyperuricemic with gout. Methods: This randomized control study included 200 hyperuricemic patients with gout, at Multi-center study including Outdoor Departments of Medicine from four different hospitals of Lahore, Pakistan. Patients age range 18-50 years diagnosis wi...
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This study was aimed at evaluating the effects of Selaginella moellendorffii Hieron. (SM) on gouty arthritis and getting an insight of the possible mechanisms. HPLC method was developed for chemical analysis. The paw oedema, the neutrophil accumulation, inflammatory mediators, lipid peroxidation, and histopathological changes of the joints were analyzed in gouty arthritis rat model, and the kid...
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At the 661st Meeting of the Biochemical Society, held at Bath, the Host Colloquium, a joint meeting with the Society for Free Radical Research, took place on 10th and 11th April 1997. Its title was ‘Xanthine oxidase: enzymology and pathophysiology’. The two aspects of xanthine oxidase research specified in the Colloquium title have developed remarkably separately, and, for a number of reasons, ...
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In the course of investigations regarding the effects of various chemical agents on neoplast,ic purine metabolism, it was observed that hydroxylamine prevents the accumulation of uric acid or allantoin that normally occurs upon incubation of crude tissue homogenates. Subsequent studies, reported in this paper, demonstrate that hydroxylamine is a competitive inhibitor of xanthine oxidase activit...
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The participation of metals in the action ofmetalloflavoproteins is the subject of much controversy, and it has recently been concluded by Singer & Massey (1957) that only for nitrate reductase has strong evidence been presented for valency changes in the metal in the course of the enzymic reactions. Studies on the function of the molybdenum, iron and flavinadenine dinucleotide of xanthine oxid...
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ژورنال
عنوان ژورنال: GOUT AND NUCLEIC ACID METABOLISM
سال: 2011
ISSN: 2186-6368,1344-9796
DOI: 10.6032/gnam.35.211